The Eukaryotic Cell Cycle and Cancer

Navigate to the following site.  https://www.biointeractive.org/classroom-resources/eukaryotic-cell-cycle-and-cancer

Click on the link to "Launch Interactive"

Use the interactive activity to answer the following questions in the your notebook:

The Eukaryotic Cell Cycle

• What is the significance on Cell Division? 
• Cells can Divide, Differentiate or Die. Explain Differentiation. 
• Define the following Terms: Mitosis, Interphase, Apoptosis, Kinase, Cell Cycle Regulators
• Diagram and Explain what happens in each phase (G1, S, G2) of the Interphase cycle. 
• Diagram and Explain what happens during Mitosis 
• Explain the purpose of the ‘checkpoints” indicated on the interactive diagram. 
• What is the G0 phase in the cell cycle? What determines if a cell goes to the G0 phase? 
• What is one potential outcome when errors occur in this highly regulated cell cycle process? 

Errors in Translation: Cancer

• What happens when cell regulators fail to function properly?
• Explain the difference between Stimulatory and Inhibitory proteins and provide an example of each.
• Describe two reasons cells can form tumors?
• What are oncogenes and how do they affect the cell cycle?
• Tumor suppressor genes inhibit the cell cycle. How do mutated tumor suppressor genes affect the cell cycle?